Improved performance of the modified Hodge test with MacConkey agar for screening carbapenemase-producing Gram-negative bacilli
20 ноября 2020 года
12:12
Improved performance of the modified Hodge test with MacConkey agar for screening carbapenemase-producing Gram-negative bacilli
Текст новости:
Title: Improved performance of the modified Hodge test with MacConkey agar for screening carbapenemase-producing Gram-negative bacilli
Author, co-author: Lee, K.; Kim, C. K.; Yong, D.; Jeong, S. H.; Yum, J. H.; Seo, Y. H.; Docquier, Jean-Denis; Chong, Y.
Abstract: The detection of carbapenemases in Gram-negative bacilli is important for optimal patient treatment and to control spread of the resistance. The modified Hodge test can detect carbapenemase-producing Gram-negative bacilli. In this study, we compared the performance of MacConkey agar and Mueller-Hinton agar for metallo-β-lactamase (MBL) and OXA carbapenemase screening. Overall, the performance of Hodge test was better with MacConkey agar due to enhanced release of β-lactamases from the cells in the presence of bile compounds. Concomitant use of the modified Hodge test could resolve most of the problems with uncertain double-disk synergy tests in MBL detection. © 2010 Elsevier B.V.

Текст со страницы (автоматическое получение):
Improved performance of the modified Hodge test with MacConkey agar for screening carbapenemase-producing Gram-negative bacilli
Language :
Publication date :
Keywords :
[en] Carbapenemase screening ; MacConkey agar ; Modified Hodge test ; Gram negative bacterium ; Agar ; Anti-Bacterial Agents ; Bacterial Proteins ; Culture Media ; Gram-Negative Bacteria ; Gram-Negative Bacterial Infections ; Humans ; Imipenem ; Mass Screening ; Microbial Sensitivity Tests ; Bacilli (class) ; Negibacteria
Abstract :
[en] The detection of carbapenemases in Gram-negative bacilli is important for optimal patient treatment and to control spread of the resistance. The modified Hodge test can detect carbapenemase-producing Gram-negative bacilli. In this study, we compared the performance of MacConkey agar and Mueller-Hinton agar for metallo-β-lactamase (MBL) and OXA carbapenemase screening. Overall, the performance of Hodge test was better with MacConkey agar due to enhanced release of β-lactamases from the cells in the presence of bile compounds. Concomitant use of the modified Hodge test could resolve most of the problems with uncertain double-disk synergy tests in MBL detection. © 2010 Elsevier B.V.
Permalink :
Автоматическая система мониторинга и отбора информации
Источник
Другие материалы рубрики
★★★  20 ноября 2020 года
13:12
Eosinophils inhibit mesothelioma chemotherapy
★★★★  19 ноября 2020 года
18:31
Le Centre d'accompagnement des Transidentités du CHU de Liège